Query   'EBH domain'  matched   7 Records

Record No : 1

Instance ID10988
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceRPSQIPTPVNN
Bait Uniprot AccessionP25054
Bait Uniprot IdentifierAPC_HUMAN
Bait Gene NameAPC
Bait OrganismHomo sapiens (Human)
Sequence Position2801-2811
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)NMR; Pull down; Classical fluorescence spectroscopy; ITC; Mutation analysis
Interaction ID20988
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15616574
CommentsThe C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the C-terminal SxIP motif of human Adenomatous polyposis coli (APC) tumor suppressor

Record No : 2

Instance ID10989
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceKRSKIPRSQGC
Bait Uniprot AccessionO75122
Bait Uniprot IdentifierCLAP2_HUMAN
Bait Gene NameCLASP2
Bait OrganismHomo sapiens (Human)
Sequence Position492-502
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Classical fluorescence spectroscopy
Interaction ID20989
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19632184
CommentsThe C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the SxIP motif (492-502) in the central part of human CLIP-associating protein 2 (CLASP2)

Record No : 3

Instance ID10990
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceRSSRIPRPSVS
Bait Uniprot AccessionO75122
Bait Uniprot IdentifierCLAP2_HUMAN
Bait Gene NameCLASP2
Bait OrganismHomo sapiens (Human)
Sequence Position515-525
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Classical fluorescence spectroscopy; Mutation analysis
Interaction ID20990
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19632184
CommentsThe C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the SxIP motif (515-525) in the central part of human CLIP-associating protein 2 (CLASP2)

Record No : 4

Instance ID10991
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceQASRNTRIPHLAGKK
Bait Uniprot AccessionQ13586
Bait Uniprot IdentifierSTIM1_HUMAN
Bait Gene NameSTIM1
Bait OrganismHomo sapiens (Human)
Sequence Position637-651
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Classical fluorescence spectroscopy; Mutation analysis
Interaction ID20991
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19632184
CommentsThe C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the SxIP motif of human Stromal interaction molecule 1 (STIM1)

Record No : 5

Instance ID10992
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceRRSVNSKIPAPK
Bait Uniprot AccessionQ99661
Bait Uniprot IdentifierKIF2C_HUMAN
Bait Gene NameKIF2C
Bait OrganismHomo sapiens (Human)
Sequence Position93-104
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Classical fluorescence spectroscopy; Pull down; Mutation analysis
Interaction ID20992
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19632184
CommentsThe C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the SxIP motif of human Kinesin-like protein KIF2C

Record No : 6

Instance ID10993
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceSTAKPSKIPTPQRK
Bait Uniprot AccessionQ03001
Bait Uniprot IdentifierDYST_HUMAN
Bait Gene NameDST
Bait OrganismHomo sapiens (Human)
Sequence Position7545-7558
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; Classical fluorescence spectroscopy; Pull down; ITC; Mutation analysis
Interaction ID20993
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19632184
CommentsThe C-terminal EBH domain of human End-binding protein 1 (EB1) or MAPRE1 binds to the SxIP motif of human Dystonin (DST)

Record No : 7

Instance ID12191
Regular Expression([KR][^ED]{0,5}[ST]xIP[^ED]{5,5})|([^ED]{5,5}[ST]xIP[^ED]{0,5}[KR])
Motif InstanceKPSKIPVYTKR
Bait Uniprot AccessionQ4U9M9
Bait Uniprot Identifier104K_THEAN
Bait Gene NameTA08425
Bait OrganismTheileria annulata
Sequence Position564-574
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Pull down(GST tag)
Interaction ID22191
Interacting DomainEBH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23675298
CommentsThe C-terminal EBH domain of mouse End-binding protein 1 (EB1) or Mapre1 binds to the SxIP motif of 104 kDa microneme/rhoptry antigen (p104) of Theileria annulata, a tick-borne Apicomplexan parasite




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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)